PDK4 anticorps
Aperçu rapide pour PDK4 anticorps (ABIN3028962)
Antigène
Voir toutes PDK4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified
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Immunogène
- A purified His-tagged recombinant protein fragment was used to produced this monoclonal PDK4 antibody.
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Isotype
- IgG1
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Indications d'application
- Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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Autre désignation
- PDK4
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Sujet
- This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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UniProt
- Q16654
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Pathways
- Signalisation PI3K-Akt, Signalisation Hedgehog, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, L'effet Warburg
Antigène
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